The Internet, PCs, World Wide Web, cloud computing, smartphones, sensors, and social media have reshaped how we live, work, learn, and play, but a new set of technologies promises even greater transformation of our lives and world. Emerging AI and IoT technologies, sensors and edge computing, practical AR/VR/XR and spatial web technologies, digital twins, quantum computing, and more are poised for revolutionary impact in business, education, research, health, transportation, entertainment, and more. We will project how this will lead to energizing and enhancing human endeavors and opportunities, and share what individuals, companies, organizations, and governments should do now to prepare, innovate, and thrive!